Next-generation phenotyping using computer vision algorithms in rare genomic neurodevelopmental disorders
نویسندگان
چکیده
منابع مشابه
Evaluating rare variants in complex disorders using next-generation sequencing.
Determining the genetic architecture of liability for complex neuropsychiatric disorders like autism spectrum disorders and schizophrenia poses a tremendous challenge for contemporary biomedical research. Here we discuss how genetic studies first tested, and rejected, the hypothesis that common variants with large effects account for the prevalence of these disorders. We then explore how the di...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2018
ISSN: 1098-3600,1530-0366
DOI: 10.1038/s41436-018-0404-y